{"id": "OSDR-FRAG-00001", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for IGFBP7 in homo_sapiens :: cells_cultured?", "gene": "IGFBP7", "organism": "homo_sapiens", "tissue": "cells_cultured", "context": "homo_sapiens::cells_cultured", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-863", "OSD-871"], "min_abs_log2FC": 1.8534, "max_abs_log2FC": 1.9112, "max_q": 0.025232, "discordant": true}, "provenance": [{"osd": "OSD-863", "log2FC_SF_vs_GC": 1.9112, "q": 0.00311419641912841, "contrast": "(no known diseases & Space Flight & with microglia)v(no known diseases & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-716_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-871", "log2FC_SF_vs_GC": -1.8534, "q": 0.0252317843594583, "contrast": "(Sporadic Parkinson disease & Space Flight & with microglia)v(Sporadic Parkinson disease & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-720_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00002", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ANXA1 in homo_sapiens :: cells_cultured?", "gene": "ANXA1", "organism": "homo_sapiens", "tissue": "cells_cultured", "context": "homo_sapiens::cells_cultured", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-863", "OSD-871"], "min_abs_log2FC": 1.0157, "max_abs_log2FC": 1.5268, "max_q": 0.046046, "discordant": true}, "provenance": [{"osd": "OSD-863", "log2FC_SF_vs_GC": 1.5268, "q": 0.0460458614673409, "contrast": "(no known diseases & Space Flight & with microglia)v(no known diseases & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-716_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-871", "log2FC_SF_vs_GC": -1.0157, "q": 0.0261762436222637, "contrast": "(Sporadic Parkinson disease & Space Flight & with microglia)v(Sporadic Parkinson disease & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-720_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00003", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for SPH93 in drosophila_melanogaster :: whole_organism?", "gene": "SPH93", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-1", "OSD-588"], "min_abs_log2FC": 3.6534, "max_abs_log2FC": 3.6648, "max_q": 0.000175, "discordant": true}, "provenance": [{"osd": "OSD-1", "log2FC_SF_vs_GC": -3.6648, "q": 0.000175337239254259, "contrast": "(Space Flight & infected with Beauveria bassiana)v(Ground Control & infected with Beauveria bassiana)", "orientation_sign_applied": 1, "source_file": "GLDS-1_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 3.6534, "q": 3.90676295544459e-31, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00004", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Spn88Eb in drosophila_melanogaster :: whole_organism?", "gene": "Spn88Eb", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-1", "OSD-588"], "min_abs_log2FC": 2.8664, "max_abs_log2FC": 3.6318, "max_q": 0.000298, "discordant": true}, "provenance": [{"osd": "OSD-1", "log2FC_SF_vs_GC": -2.8664, "q": 0.000297881506813778, "contrast": "(Space Flight & infected with Beauveria bassiana)v(Ground Control & infected with Beauveria bassiana)", "orientation_sign_applied": 1, "source_file": "GLDS-1_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 3.6318, "q": 0.0, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00005", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for CG18563 in drosophila_melanogaster :: whole_organism?", "gene": "CG18563", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-1", "OSD-588"], "min_abs_log2FC": 2.5062, "max_abs_log2FC": 3.4085, "max_q": 4e-06, "discordant": true}, "provenance": [{"osd": "OSD-1", "log2FC_SF_vs_GC": -3.4085, "q": 4.27070187615697e-06, "contrast": "(Space Flight & infected with Beauveria bassiana)v(Ground Control & infected with Beauveria bassiana)", "orientation_sign_applied": 1, "source_file": "GLDS-1_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 2.5062, "q": 1.13310837016818e-07, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00006", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for MESK4|CG31274 in drosophila_melanogaster :: whole_organism?", "gene": "MESK4|CG31274", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-278", "OSD-588"], "min_abs_log2FC": 2.3679, "max_abs_log2FC": 22.1846, "max_q": 0.001567, "discordant": true}, "provenance": [{"osd": "OSD-278", "log2FC_SF_vs_GC": 22.1846, "q": 2.88816226508809e-09, "contrast": "(Space Flight & Infected with Serratia marcescens)v(Ground Control & Infected with Serratia marcescens)", "orientation_sign_applied": 1, "source_file": "GLDS-278_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": -2.3679, "q": 0.00156725883886733, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00007", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for NimB3 in drosophila_melanogaster :: whole_organism?", "gene": "NimB3", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-1", "OSD-588"], "min_abs_log2FC": 2.0837, "max_abs_log2FC": 2.2436, "max_q": 0.012908, "discordant": true}, "provenance": [{"osd": "OSD-1", "log2FC_SF_vs_GC": -2.2436, "q": 0.0129084379492965, "contrast": "(Space Flight & infected with Beauveria bassiana)v(Ground Control & infected with Beauveria bassiana)", "orientation_sign_applied": 1, "source_file": "GLDS-1_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 2.0837, "q": 1.92212398537108e-87, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00008", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for EREG in homo_sapiens :: cells?", "gene": "EREG", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-323", "OSD-546", "OSD-635"], "min_abs_log2FC": 1.7966, "max_abs_log2FC": 2.9567, "max_q": 0.03578, "discordant": true}, "provenance": [{"osd": "OSD-323", "log2FC_SF_vs_GC": 1.7966, "q": 0.0357802844619784, "contrast": "(Space Flight & Infected with Salmonella Typhimurium)v(Ground Control & Infected with Salmonella Typhimurium)", "orientation_sign_applied": 1, "source_file": "GLDS-323_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-546", "log2FC_SF_vs_GC": -2.9567, "q": 1.43256773667288e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -2.6875, "q": 3.88915050094602e-31, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00009", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for SLC40A1 in homo_sapiens :: cells?", "gene": "SLC40A1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-323", "OSD-546", "OSD-635"], "min_abs_log2FC": 0.6347, "max_abs_log2FC": 2.0271, "max_q": 0.032548, "discordant": true}, "provenance": [{"osd": "OSD-323", "log2FC_SF_vs_GC": -2.0271, "q": 0.00549571442789703, "contrast": "(Space Flight & Infected with Salmonella Typhimurium)v(Ground Control & Infected with Salmonella Typhimurium)", "orientation_sign_applied": 1, "source_file": "GLDS-323_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-546", "log2FC_SF_vs_GC": 0.7908, "q": 0.00895061900762667, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -0.6347, "q": 0.0325478199419779, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00010", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for PPP1R2 in homo_sapiens :: cells?", "gene": "PPP1R2", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-323", "OSD-546", "OSD-635"], "min_abs_log2FC": 0.4576, "max_abs_log2FC": 1.9005, "max_q": 0.035695, "discordant": true}, "provenance": [{"osd": "OSD-323", "log2FC_SF_vs_GC": 1.9005, "q": 0.0168974903119217, "contrast": "(Space Flight & Infected with Salmonella Typhimurium)v(Ground Control & Infected with Salmonella Typhimurium)", "orientation_sign_applied": 1, "source_file": "GLDS-323_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-546", "log2FC_SF_vs_GC": -0.4642, "q": 0.0196461487794798, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 0.4576, "q": 0.03569479982674, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00011", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for CD248 in homo_sapiens :: cells?", "gene": "CD248", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 3.975, "max_abs_log2FC": 4.4385, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 3.975, "q": 4.53877241479032e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.4385, "q": 3.20518876009915e-16, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00012", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for IL7R in homo_sapiens :: cells?", "gene": "IL7R", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 3.5453, "max_abs_log2FC": 4.0054, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 3.5453, "q": 4.53877241479032e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.0054, "q": 4.64029387174939e-30, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00013", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for SPINK1 in homo_sapiens :: cells?", "gene": "SPINK1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 3.2022, "max_abs_log2FC": 3.4249, "max_q": 3e-05, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -3.2022, "q": 2.95918722518438e-05, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 3.4249, "q": 1.16164479590006e-06, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00014", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for F2R in homo_sapiens :: cells?", "gene": "F2R", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-323", "OSD-546"], "min_abs_log2FC": 3.0513, "max_abs_log2FC": 4.1592, "max_q": 0.003915, "discordant": true}, "provenance": [{"osd": "OSD-323", "log2FC_SF_vs_GC": -4.1592, "q": 0.0039151885179006, "contrast": "(Space Flight & Infected with Salmonella Typhimurium)v(Ground Control & Infected with Salmonella Typhimurium)", "orientation_sign_applied": 1, "source_file": "GLDS-323_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-546", "log2FC_SF_vs_GC": 3.0513, "q": 9.94433875152757e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00015", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for CLDN11 in homo_sapiens :: cells?", "gene": "CLDN11", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.9524, "max_abs_log2FC": 4.5287, "max_q": 4e-06, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.9524, "q": 4.26466250646791e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.5287, "q": 2.48589417987775e-97, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00016", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for GASK1B in homo_sapiens :: cells?", "gene": "GASK1B", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.9077, "max_abs_log2FC": 7.3498, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.9077, "q": 1.98614126205474e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -7.3498, "q": 1.25335604011193e-98, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00017", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for PIEZO2 in homo_sapiens :: cells?", "gene": "PIEZO2", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.8908, "max_abs_log2FC": 2.938, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.938, "q": 1.1163753574607e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -2.8908, "q": 3.20320933351473e-11, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00018", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for FGF7 in homo_sapiens :: cells?", "gene": "FGF7", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.8902, "max_abs_log2FC": 3.2776, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.8902, "q": 6.83867436802839e-08, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.2776, "q": 1.03428625584859e-35, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00019", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for RAB27B in homo_sapiens :: cells?", "gene": "RAB27B", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.864, "max_abs_log2FC": 3.434, "max_q": 2.8e-05, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.864, "q": 2.75783334890849e-05, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.434, "q": 1.32408400209781e-75, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00020", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for BRINP1 in homo_sapiens :: cells?", "gene": "BRINP1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.8484, "max_abs_log2FC": 5.9898, "max_q": 0.000133, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.8484, "q": 1.80836892055268e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -5.9898, "q": 0.000133139583005455, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00021", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for DEPTOR in homo_sapiens :: cells?", "gene": "DEPTOR", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.7323, "max_abs_log2FC": 4.4686, "max_q": 6e-06, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.7323, "q": 6.33506286143072e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.4686, "q": 1.3977085190265e-61, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00022", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ABCA8 in homo_sapiens :: cells?", "gene": "ABCA8", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.6934, "max_abs_log2FC": 3.0425, "max_q": 2e-06, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.6934, "q": 2.29285388669615e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.0425, "q": 1.82681292478803e-29, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00023", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AKR1C2 in homo_sapiens :: cells?", "gene": "AKR1C2", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.6677, "max_abs_log2FC": 3.2026, "max_q": 2.6e-05, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.6677, "q": 2.63243924249451e-05, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.2026, "q": 2.10175239031349e-57, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00024", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for HID1 in homo_sapiens :: cells?", "gene": "HID1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.6525, "max_abs_log2FC": 3.5744, "max_q": 7e-06, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -2.6525, "q": 6.50875999356165e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 3.5744, "q": 5.81634601969281e-25, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00025", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for PCDH18 in homo_sapiens :: cells?", "gene": "PCDH18", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.5564, "max_abs_log2FC": 3.0234, "max_q": 1e-06, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.5564, "q": 8.46499881914036e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.0234, "q": 1.48779748269738e-20, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00026", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ANGPT1 in homo_sapiens :: cells?", "gene": "ANGPT1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.4623, "max_abs_log2FC": 2.603, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.4623, "q": 4.23489285163277e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -2.603, "q": 1.53501521117504e-15, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00027", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for PLK2 in homo_sapiens :: cells?", "gene": "PLK2", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.4364, "max_abs_log2FC": 2.5372, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.5372, "q": 2.27749601267732e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -2.4364, "q": 1.46522310424225e-48, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00028", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for CMKLR1 in homo_sapiens :: cells?", "gene": "CMKLR1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.428, "max_abs_log2FC": 5.4475, "max_q": 0.003876, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.428, "q": 0.00387568172859837, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -5.4475, "q": 0.000244148651153476, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00029", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ABCA9 in homo_sapiens :: cells?", "gene": "ABCA9", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.4138, "max_abs_log2FC": 2.4709, "max_q": 3e-06, "discordant": true}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.4709, "q": 3.44694017441206e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -2.4138, "q": 1.52783621720059e-15, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00030", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Oscp1 in mus_musculus :: thymus?", "gene": "Oscp1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 1.5619, "max_abs_log2FC": 3.6097, "max_q": 0.047417, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 1.5619, "q": 0.0474171182918736, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -3.6097, "q": 0.0178104157273343, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.7656, "q": 0.000654620477216276, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00031", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Hsph1 in mus_musculus :: thymus?", "gene": "Hsph1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-4", "OSD-421", "OSD-515"], "min_abs_log2FC": 1.0793, "max_abs_log2FC": 1.8927, "max_q": 0.008216, "discordant": true}, "provenance": [{"osd": "OSD-4", "log2FC_SF_vs_GC": -1.8927, "q": 0.00690278769274297, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-4_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 1.0793, "q": 0.00821646605097406, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.7291, "q": 0.000521191024040509, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00032", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Ccdc168 in mus_musculus :: thymus?", "gene": "Ccdc168", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.8824, "max_abs_log2FC": 1.6898, "max_q": 0.034144, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.6898, "q": 0.0243988899855097, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 1.2338, "q": 0.0085970328624711, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.8824, "q": 0.0341437406478155, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00033", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for L3mbtl3 in mus_musculus :: thymus?", "gene": "L3mbtl3", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.7428, "max_abs_log2FC": 0.8325, "max_q": 0.01024, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -0.7664, "q": 0.0102397144602693, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.8325, "q": 0.00217539213219231, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.7428, "q": 0.0100504395490014, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00034", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Nabp1 in mus_musculus :: thymus?", "gene": "Nabp1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.5664, "max_abs_log2FC": 1.5001, "max_q": 0.010936, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.5001, "q": 0.00178230755118857, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.6644, "q": 0.0109359486971451, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.5664, "q": 0.00871247318867177, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00035", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Slc40a1 in mus_musculus :: thymus?", "gene": "Slc40a1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.5227, "max_abs_log2FC": 0.98, "max_q": 0.039467, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -0.8221, "q": 0.0145530227218548, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.98, "q": 0.000770494614507602, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 0.5227, "q": 0.039467267930772, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00036", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Dpysl2 in mus_musculus :: thymus?", "gene": "Dpysl2", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.5081, "max_abs_log2FC": 0.9623, "max_q": 0.032715, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 0.5443, "q": 0.0327147234028966, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -0.9623, "q": 0.0172870297800985, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.5081, "q": 0.0304548046490291, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00037", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Zfp322a in mus_musculus :: thymus?", "gene": "Zfp322a", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.4583, "max_abs_log2FC": 1.005, "max_q": 0.032125, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.005, "q": 0.00843824952091945, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.6194, "q": 0.0321248027930407, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.4583, "q": 0.0235242981140366, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00038", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Slc38a2 in mus_musculus :: thymus?", "gene": "Slc38a2", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.4188, "max_abs_log2FC": 0.7556, "max_q": 0.039392, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -0.7556, "q": 0.0101964161038458, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.6282, "q": 0.00646051388912817, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.4188, "q": 0.0393920353931794, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00039", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Vps37a in mus_musculus :: thymus?", "gene": "Vps37a", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.3901, "max_abs_log2FC": 1.0558, "max_q": 0.040877, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.0558, "q": 0.00798882894797825, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.6703, "q": 0.0408773751591977, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.3901, "q": 0.0251421514202591, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00040", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Wfdc12 in mus_musculus :: thymus?", "gene": "Wfdc12", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 2.797, "max_abs_log2FC": 2.7994, "max_q": 0.043314, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -2.797, "q": 0.037760930443283, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 2.7994, "q": 0.0433142633233723, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00041", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Ush2a in mus_musculus :: thymus?", "gene": "Ush2a", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 2.4243, "max_abs_log2FC": 2.6988, "max_q": 0.039916, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -2.4243, "q": 0.0384465491854208, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 2.6988, "q": 0.0399155779509964, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00042", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Rhox8 in mus_musculus :: thymus?", "gene": "Rhox8", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-421"], "min_abs_log2FC": 2.0442, "max_abs_log2FC": 3.2509, "max_q": 0.031101, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -3.2509, "q": 0.0311014515967589, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 2.0442, "q": 0.0113894557787947, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00043", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Acan in mus_musculus :: thymus?", "gene": "Acan", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.9152, "max_abs_log2FC": 4.1219, "max_q": 0.010757, "discordant": true}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -4.1219, "q": 0.00700469692835756, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.9152, "q": 0.0107570452408353, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00044", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Fpr1 in mus_musculus :: thymus?", "gene": "Fpr1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.9126, "max_abs_log2FC": 1.9686, "max_q": 0.016529, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 1.9126, "q": 0.0165292819082078, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.9686, "q": 0.00786637998219902, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00045", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Gm26225 in mus_musculus :: thymus?", "gene": "Gm26225", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.7905, "max_abs_log2FC": 1.9566, "max_q": 0.043079, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.7905, "q": 0.0117936138408213, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.9566, "q": 0.0430794078676586, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00046", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Trav6-7-dv9 in mus_musculus :: thymus?", "gene": "Trav6-7-dv9", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-421"], "min_abs_log2FC": 1.638, "max_abs_log2FC": 1.6844, "max_q": 0.041159, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.6844, "q": 0.0285729420793772, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 1.638, "q": 0.0411593996356781, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00047", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Igkv8-21 in mus_musculus :: thymus?", "gene": "Igkv8-21", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.4285, "max_abs_log2FC": 2.764, "max_q": 0.045594, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 2.764, "q": 0.0135010372789587, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.4285, "q": 0.0455941105785927, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00048", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Cd46 in mus_musculus :: thymus?", "gene": "Cd46", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-421"], "min_abs_log2FC": 1.3369, "max_abs_log2FC": 1.6142, "max_q": 0.033862, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.6142, "q": 0.00843824952091945, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 1.3369, "q": 0.0338615345554877, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00049", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Mst1 in mus_musculus :: thymus?", "gene": "Mst1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.2651, "max_abs_log2FC": 5.4132, "max_q": 0.022017, "discordant": true}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -5.4132, "q": 0.0220174981744726, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.2651, "q": 0.00235609465565922, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00050", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Ptger3 in mus_musculus :: thymus?", "gene": "Ptger3", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-4", "OSD-515"], "min_abs_log2FC": 1.2504, "max_abs_log2FC": 1.312, "max_q": 0.044267, "discordant": true}, "provenance": [{"osd": "OSD-4", "log2FC_SF_vs_GC": -1.2504, "q": 0.0412357519303575, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-4_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.312, "q": 0.0442665834381932, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00051", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Slc28a2b in mus_musculus :: thymus?", "gene": "Slc28a2b", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.1857, "max_abs_log2FC": 1.5458, "max_q": 0.016164, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.1857, "q": 0.0161642575138833, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.5458, "q": 0.00145876313860849, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00052", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Adamts6 in mus_musculus :: thymus?", "gene": "Adamts6", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-421"], "min_abs_log2FC": 1.1666, "max_abs_log2FC": 1.3598, "max_q": 0.011578, "discordant": true}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.3598, "q": 0.00818415765907381, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 1.1666, "q": 0.0115776621381635, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00053", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Elovl3 in mus_musculus :: liver?", "gene": "Elovl3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 5, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-242", "OSD-245"], "min_abs_log2FC": 1.4516, "max_abs_log2FC": 2.7918, "max_q": 0.037339, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.8779, "q": 0.000204745573595616, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 2.7918, "q": 0.00630990965391496, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.6312, "q": 0.0373391616623034, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -1.4551, "q": 6.11900883960559e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-245", "log2FC_SF_vs_GC": 1.4516, "q": 0.0162677166027922, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-245_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00054", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Pla2g12a in mus_musculus :: liver?", "gene": "Pla2g12a", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 5, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.7544, "max_abs_log2FC": 1.1646, "max_q": 0.005625, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.7544, "q": 0.000495032121068919, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.0798, "q": 0.000119066006793052, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.1646, "q": 3.63446184746816e-06, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.0931, "q": 0.00562468393716976, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 1.1589, "q": 0.000370583931280553, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00055", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Acadm in mus_musculus :: liver?", "gene": "Acadm", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 5, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.4387, "max_abs_log2FC": 1.0494, "max_q": 0.034225, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.5799, "q": 0.000389796441330963, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.4387, "q": 0.0342248406066876, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.5964, "q": 0.000245674676522589, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 0.981, "q": 0.000131793209895672, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 1.0494, "q": 0.000616873794237162, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00056", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Gstt2 in mus_musculus :: liver?", "gene": "Gstt2", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 5, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.4118, "max_abs_log2FC": 1.5601, "max_q": 0.0301, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.4118, "q": 0.0301000098418233, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.5601, "q": 1.27728935569561e-11, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.4693, "q": 2.47492515183656e-09, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.4449, "q": 0.0138866894611645, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 1.0631, "q": 0.000206191416384209, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00057", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Pnpla5 in mus_musculus :: liver?", "gene": "Pnpla5", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-48", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 4.2511, "max_abs_log2FC": 5.7803, "max_q": 0.009227, "discordant": true}, "provenance": [{"osd": "OSD-48", "log2FC_SF_vs_GC": 4.2511, "q": 7.66756840656923e-06, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 5.067, "q": 4.89395841762655e-06, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -5.7803, "q": 0.00162743901608446, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -4.5109, "q": 0.00922660631999747, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00058", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Chrna4 in mus_musculus :: liver?", "gene": "Chrna4", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-48", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 2.4833, "max_abs_log2FC": 3.3032, "max_q": 0.009227, "discordant": true}, "provenance": [{"osd": "OSD-48", "log2FC_SF_vs_GC": 2.4833, "q": 0.00641572527857669, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 2.7792, "q": 0.00422449139490094, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -3.3032, "q": 0.000305475886053394, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -2.9338, "q": 0.00922660631999747, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00059", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Pnpla3 in mus_musculus :: liver?", "gene": "Pnpla3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 1.1519, "max_abs_log2FC": 2.4833, "max_q": 0.040307, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -1.1519, "q": 0.0323652395411265, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 2.4833, "q": 0.0403073236359474, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.9626, "q": 0.00320294152997217, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.9433, "q": 0.00507491318395021, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00060", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Csad in mus_musculus :: liver?", "gene": "Csad", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-168", "OSD-173", "OSD-242", "OSD-245"], "min_abs_log2FC": 1.147, "max_abs_log2FC": 1.7961, "max_q": 0.043106, "discordant": true}, "provenance": [{"osd": "OSD-168", "log2FC_SF_vs_GC": -1.147, "q": 0.0147068916128307, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.4887, "q": 0.0220057076311483, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 1.7961, "q": 0.000433847066758027, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-245", "log2FC_SF_vs_GC": 1.2534, "q": 0.0431059027385122, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-245_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00061", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Slc22a5 in mus_musculus :: liver?", "gene": "Slc22a5", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 1.1328, "max_abs_log2FC": 2.5014, "max_q": 0.018154, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.322, "q": 2.87739993679183e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.1328, "q": 0.018154143665455, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.1489, "q": 0.0014766421509682, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.5014, "q": 5.02150157387857e-10, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00062", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Chka in mus_musculus :: liver?", "gene": "Chka", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-245"], "min_abs_log2FC": 1.0612, "max_abs_log2FC": 1.7914, "max_q": 0.027564, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -1.1629, "q": 0.00271557105864354, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 1.7885, "q": 0.000382891687140789, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.7914, "q": 0.00263372707158623, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-245", "log2FC_SF_vs_GC": 1.0612, "q": 0.0275641304695361, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-245_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00063", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Shfl in mus_musculus :: liver?", "gene": "Shfl", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-242"], "min_abs_log2FC": 0.9674, "max_abs_log2FC": 1.2763, "max_q": 0.02426, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -1.0429, "q": 0.00480240460017781, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 1.1474, "q": 0.0242598241526999, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.2763, "q": 6.27935625320259e-07, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -0.9674, "q": 0.0012188997369517, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00064", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Nr1d1 in mus_musculus :: liver?", "gene": "Nr1d1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-48", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.9565, "max_abs_log2FC": 3.5711, "max_q": 0.040476, "discordant": true}, "provenance": [{"osd": "OSD-48", "log2FC_SF_vs_GC": -1.4082, "q": 0.00360619163369635, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.9565, "q": 0.0404758630350281, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -3.5711, "q": 0.00222644029536885, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 1.3004, "q": 0.0282706020211757, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00065", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Sgk2 in mus_musculus :: liver?", "gene": "Sgk2", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.9557, "max_abs_log2FC": 1.1869, "max_q": 0.037976, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.1869, "q": 0.00114471262606994, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.9557, "q": 6.43712249106598e-05, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.0159, "q": 0.000896332119136534, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 0.9939, "q": 0.0379760883138132, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00066", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for G0s2 in mus_musculus :: liver?", "gene": "G0s2", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.9149, "max_abs_log2FC": 2.1155, "max_q": 0.037082, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.136, "q": 0.00153048916402135, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.9149, "q": 0.0370821135514569, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.2778, "q": 0.0188024140422249, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.1155, "q": 1.3504076851926e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00067", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Plin2 in mus_musculus :: liver?", "gene": "Plin2", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.8718, "max_abs_log2FC": 1.1991, "max_q": 0.002058, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.8718, "q": 6.68512535096894e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.8839, "q": 0.00178644842893448, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.8737, "q": 0.000245511957970077, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.1991, "q": 0.00205751019677162, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00068", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Hsd3b5 in mus_musculus :: liver?", "gene": "Hsd3b5", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-242"], "min_abs_log2FC": 0.8503, "max_abs_log2FC": 5.1955, "max_q": 0.037707, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.8503, "q": 0.0373222572548429, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 5.1955, "q": 0.0046244793875288, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 2.4934, "q": 0.0377068755266836, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -1.2642, "q": 0.00129756681940765, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00069", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Ypel2 in mus_musculus :: liver?", "gene": "Ypel2", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.8368, "max_abs_log2FC": 1.2666, "max_q": 0.04797, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -1.1702, "q": 0.000495032121068919, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 1.1035, "q": 0.000388687859281726, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 0.8368, "q": 0.047969958607641, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.2666, "q": 0.00229872520788156, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00070", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Gpat3 in mus_musculus :: liver?", "gene": "Gpat3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.8276, "max_abs_log2FC": 2.6755, "max_q": 0.010999, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 2.0694, "q": 2.38654314822979e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.8276, "q": 0.0109994841603227, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.0706, "q": 3.31265753036643e-05, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.6755, "q": 8.97886623943018e-17, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00071", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Cpt1a in mus_musculus :: liver?", "gene": "Cpt1a", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.8105, "max_abs_log2FC": 1.2302, "max_q": 0.02171, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.8105, "q": 7.16210787960705e-06, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.0782, "q": 0.0217103932517235, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.0446, "q": 0.000737149567659394, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.2302, "q": 1.19796916264195e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00072", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Acot4 in mus_musculus :: liver?", "gene": "Acot4", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.7965, "max_abs_log2FC": 1.4848, "max_q": 0.007736, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.7965, "q": 0.000164699412223488, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.4848, "q": 1.56439193155664e-06, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.1434, "q": 0.00217317932742681, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.3914, "q": 0.00773554293892347, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00073", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Slc41a2 in mus_musculus :: liver?", "gene": "Slc41a2", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.7646, "max_abs_log2FC": 1.6679, "max_q": 0.046649, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.7646, "q": 0.0133666710333919, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 1.6679, "q": 4.66291382409684e-05, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.3169, "q": 0.000790089804746219, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.1226, "q": 0.0466488033166639, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00074", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Retsat in mus_musculus :: liver?", "gene": "Retsat", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-168", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.7561, "max_abs_log2FC": 1.5519, "max_q": 0.008928, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.0714, "q": 0.000275172240257109, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.7561, "q": 0.00892811562102435, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.1781, "q": 0.00113285874533968, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 1.5519, "q": 5.70695253585971e-06, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00075", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for Dio1 in mus_musculus :: liver?", "gene": "Dio1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.7097, "max_abs_log2FC": 1.7448, "max_q": 0.039956, "discordant": true}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.9226, "q": 0.000474751372913417, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 0.9357, "q": 0.0108010194259087, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 0.7097, "q": 0.0399562357425129, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -1.7448, "q": 9.48085914413756e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00076", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ATM17|M17 in arabidopsis_thaliana :: seedlings?", "gene": "ATM17|M17", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 3.5678, "max_abs_log2FC": 5.6302, "max_q": 0.044486, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.5678, "q": 0.0444864046799324, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -5.6302, "q": 5.65876974490139e-08, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00077", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for VGD1 in arabidopsis_thaliana :: seedlings?", "gene": "VGD1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 3.4205, "max_abs_log2FC": 6.8111, "max_q": 0.029706, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.4205, "q": 0.0140988145703973, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -6.8111, "q": 0.0297062717971722, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00078", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ATCSLG2|CSLG2 in arabidopsis_thaliana :: seedlings?", "gene": "ATCSLG2|CSLG2", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 3.0121, "max_abs_log2FC": 5.2291, "max_q": 0.027356, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.0121, "q": 0.0273562920419833, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -5.2291, "q": 0.0133723749986059, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00079", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for EDL3 in arabidopsis_thaliana :: seedlings?", "gene": "EDL3", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 3.0112, "max_abs_log2FC": 3.0132, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.0112, "q": 5.25192021069924e-09, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.0132, "q": 1.70557979443091e-07, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00080", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ERF54 in arabidopsis_thaliana :: seedlings?", "gene": "ERF54", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.8132, "max_abs_log2FC": 3.0926, "max_q": 8.8e-05, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.0926, "q": 1.01501096617329e-18, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.8132, "q": 8.77086229241598e-05, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00081", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ABS4|BCD1|ZF14|ZRZ in arabidopsis_thaliana :: seedlings?", "gene": "ABS4|BCD1|ZF14|ZRZ", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.5059, "max_abs_log2FC": 2.7489, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.7489, "q": 1.76850792389279e-11, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.5059, "q": 6.31467758606011e-14, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00082", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ATM4|ATMYB102|MYB102 in arabidopsis_thaliana :: seedlings?", "gene": "ATM4|ATMYB102|MYB102", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.3713, "max_abs_log2FC": 4.6537, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.3713, "q": 3.06813687217887e-12, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -4.6537, "q": 1.58649981230987e-14, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00083", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for COR78|LTI140|LTI78|RD29A in arabidopsis_thaliana :: seedlings?", "gene": "COR78|LTI140|LTI78|RD29A", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.2835, "max_abs_log2FC": 3.2713, "max_q": 2.6e-05, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.2835, "q": 2.73703473746069e-07, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.2713, "q": 2.64235118167498e-05, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00084", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AT-HSP17.6A|HSP17.6|HSP17.6A in arabidopsis_thaliana :: seedlings?", "gene": "AT-HSP17.6A|HSP17.6|HSP17.6A", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.2725, "max_abs_log2FC": 3.0278, "max_q": 0.00015, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.0278, "q": 2.48781581507983e-05, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.2725, "q": 0.000150354124407869, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00085", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for LEA7 in arabidopsis_thaliana :: seedlings?", "gene": "LEA7", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.2476, "max_abs_log2FC": 3.3845, "max_q": 0.002466, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.2476, "q": 0.00246600974383985, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.3845, "q": 0.00179273415664186, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00086", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ABR in arabidopsis_thaliana :: seedlings?", "gene": "ABR", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.241, "max_abs_log2FC": 2.5395, "max_q": 0.001956, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.5395, "q": 0.00127443842975083, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.241, "q": 0.00195593843334533, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00087", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AtERF53|ERF53 in arabidopsis_thaliana :: seedlings?", "gene": "AtERF53|ERF53", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.171, "max_abs_log2FC": 2.4305, "max_q": 9.3e-05, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.171, "q": 1.66398837938234e-12, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.4305, "q": 9.31662674948709e-05, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00088", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AtGolS2|GolS2 in arabidopsis_thaliana :: seedlings?", "gene": "AtGolS2|GolS2", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.1454, "max_abs_log2FC": 2.8015, "max_q": 1e-06, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.8015, "q": 2.68916512521313e-18, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.1454, "q": 9.44748361831311e-07, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00089", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for GDPDL6|SVL4 in arabidopsis_thaliana :: seedlings?", "gene": "GDPDL6|SVL4", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.1392, "max_abs_log2FC": 2.2692, "max_q": 0.000911, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.1392, "q": 0.000838283932992784, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.2692, "q": 0.000911326805753905, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00090", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ATTSPO|TSPO in arabidopsis_thaliana :: seedlings?", "gene": "ATTSPO|TSPO", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.1295, "max_abs_log2FC": 2.5854, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.1295, "q": 9.05531688558871e-14, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.5854, "q": 1.09757687929565e-14, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00091", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for MAPKKK18 in arabidopsis_thaliana :: seedlings?", "gene": "MAPKKK18", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.1054, "max_abs_log2FC": 3.4831, "max_q": 4e-06, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.1054, "q": 4.49756539927854e-06, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.4831, "q": 5.35068442021594e-09, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00092", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AITR5|DIG2|SLF4 in arabidopsis_thaliana :: seedlings?", "gene": "AITR5|DIG2|SLF4", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.057, "max_abs_log2FC": 3.9317, "max_q": 0.001888, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.057, "q": 4.1183727076536e-07, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.9317, "q": 0.00188755108373928, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00093", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for HAI1|SAG113 in arabidopsis_thaliana :: seedlings?", "gene": "HAI1|SAG113", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.9903, "max_abs_log2FC": 2.6365, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.9903, "q": 1.10976892956305e-07, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.6365, "q": 1.17442813816205e-13, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00094", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AtLEA4-5|LEA4-5 in arabidopsis_thaliana :: seedlings?", "gene": "AtLEA4-5|LEA4-5", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.982, "max_abs_log2FC": 3.3876, "max_q": 0.000788, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.982, "q": 0.000787798245051983, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.3876, "q": 5.5940629172438e-06, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00095", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for DREB2|DREB2A in arabidopsis_thaliana :: seedlings?", "gene": "DREB2|DREB2A", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.9245, "max_abs_log2FC": 2.0521, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.9245, "q": 3.55365389638286e-12, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.0521, "q": 9.3270133645681e-10, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00096", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AKR4C9|ChlAKR in arabidopsis_thaliana :: seedlings?", "gene": "AKR4C9|ChlAKR", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.9142, "max_abs_log2FC": 2.2002, "max_q": 0.018737, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.9142, "q": 0.0187372895588319, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.2002, "q": 0.000537371576106111, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00097", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AtBAM1|BAM1|BMY7|TR-BAMY in arabidopsis_thaliana :: seedlings?", "gene": "AtBAM1|BAM1|BMY7|TR-BAMY", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.9135, "max_abs_log2FC": 1.9251, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.9135, "q": 1.51433191641594e-10, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -1.9251, "q": 1.36984258222693e-09, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00098", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for AIP1|AtAIP1|HAI2|HON in arabidopsis_thaliana :: seedlings?", "gene": "AIP1|AtAIP1|HAI2|HON", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.8551, "max_abs_log2FC": 2.7615, "max_q": 0.0, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.8551, "q": 4.40207854732534e-11, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.7615, "q": 5.30573655414313e-09, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00099", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for ATGA2OX8|GA2OX8 in arabidopsis_thaliana :: seedlings?", "gene": "ATGA2OX8|GA2OX8", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.8486, "max_abs_log2FC": 3.0556, "max_q": 0.035597, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.8486, "q": 0.0355967324548783, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 3.0556, "q": 0.0178444143330658, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-FRAG-00100", "item_type": "fragility_trap", "prompt": "In spaceflight versus ground control, what is the direction of change for CLE1 in arabidopsis_thaliana :: seedlings?", "gene": "CLE1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "indeterminate", "accept": ["not determinable from available evidence", "evidence is contradictory", "insufficient evidence"], "reject": ["upregulated", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.8207, "max_abs_log2FC": 2.0827, "max_q": 0.000107, "discordant": true}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.8207, "q": 7.71004944115775e-05, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.0827, "q": 0.000107133493075471, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00001", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ID3 in homo_sapiens :: cells_cultured?", "gene": "ID3", "organism": "homo_sapiens", "tissue": "cells_cultured", "context": "homo_sapiens::cells_cultured", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-863", "OSD-867"], "min_abs_log2FC": 0.8736, "max_abs_log2FC": 1.7761, "max_q": 0.038831, "discordant": false}, "provenance": [{"osd": "OSD-863", "log2FC_SF_vs_GC": 1.7761, "q": 0.0388312132565428, "contrast": "(no known diseases & Space Flight & with microglia)v(no known diseases & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-716_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-867", "log2FC_SF_vs_GC": 0.8736, "q": 0.0194897028121285, "contrast": "(Space Flight & 1 week)v(Ground Control & 1 week)", "orientation_sign_applied": 1, "source_file": "GLDS-719_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00002", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ZC3H12C in homo_sapiens :: cells_cultured?", "gene": "ZC3H12C", "organism": "homo_sapiens", "tissue": "cells_cultured", "context": "homo_sapiens::cells_cultured", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-863", "OSD-871"], "min_abs_log2FC": 1.1675, "max_abs_log2FC": 1.7675, "max_q": 0.000251, "discordant": false}, "provenance": [{"osd": "OSD-863", "log2FC_SF_vs_GC": -1.7675, "q": 0.000250681039770879, "contrast": "(no known diseases & Space Flight & with microglia)v(no known diseases & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-716_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-871", "log2FC_SF_vs_GC": -1.1675, "q": 0.000102092688839804, "contrast": "(Sporadic Parkinson disease & Space Flight & with microglia)v(Sporadic Parkinson disease & Ground Control & with microglia)", "orientation_sign_applied": 1, "source_file": "GLDS-720_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00003", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for PGRP-LB in drosophila_melanogaster :: whole_organism?", "gene": "PGRP-LB", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-278", "OSD-588"], "min_abs_log2FC": 1.284, "max_abs_log2FC": 2.0356, "max_q": 0.000613, "discordant": false}, "provenance": [{"osd": "OSD-278", "log2FC_SF_vs_GC": 2.0356, "q": 0.000613413766632477, "contrast": "(Space Flight & Infected with Serratia marcescens)v(Ground Control & Infected with Serratia marcescens)", "orientation_sign_applied": 1, "source_file": "GLDS-278_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 1.284, "q": 6.65511097112167e-140, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00004", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AttA in drosophila_melanogaster :: whole_organism?", "gene": "AttA", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-278", "OSD-588"], "min_abs_log2FC": 1.9486, "max_abs_log2FC": 5.7651, "max_q": 0.0123, "discordant": false}, "provenance": [{"osd": "OSD-278", "log2FC_SF_vs_GC": 5.7651, "q": 0.0122999580617521, "contrast": "(Space Flight & Infected with Serratia marcescens)v(Ground Control & Infected with Serratia marcescens)", "orientation_sign_applied": 1, "source_file": "GLDS-278_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 1.9486, "q": 7.15259654434254e-31, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00005", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for tun in drosophila_melanogaster :: whole_organism?", "gene": "tun", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-1", "OSD-588"], "min_abs_log2FC": 0.5027, "max_abs_log2FC": 1.1628, "max_q": 0.040224, "discordant": false}, "provenance": [{"osd": "OSD-1", "log2FC_SF_vs_GC": -1.1628, "q": 0.0402242318422526, "contrast": "(Space Flight & infected with Beauveria bassiana)v(Ground Control & infected with Beauveria bassiana)", "orientation_sign_applied": 1, "source_file": "GLDS-1_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": -0.5027, "q": 2.21589794884033e-38, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00006", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for edin in drosophila_melanogaster :: whole_organism?", "gene": "edin", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-278", "OSD-588"], "min_abs_log2FC": 5.6315, "max_abs_log2FC": 8.0544, "max_q": 0.006378, "discordant": false}, "provenance": [{"osd": "OSD-278", "log2FC_SF_vs_GC": 8.0544, "q": 0.00637841070491444, "contrast": "(Space Flight & Infected with Serratia marcescens)v(Ground Control & Infected with Serratia marcescens)", "orientation_sign_applied": 1, "source_file": "GLDS-278_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 5.6315, "q": 5.64484829761171e-68, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00007", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for betaTry in drosophila_melanogaster :: whole_organism?", "gene": "betaTry", "organism": "drosophila_melanogaster", "tissue": "whole_organism", "context": "drosophila_melanogaster::whole_organism", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-278", "OSD-588"], "min_abs_log2FC": 0.7577, "max_abs_log2FC": 1.1088, "max_q": 0.000802, "discordant": false}, "provenance": [{"osd": "OSD-278", "log2FC_SF_vs_GC": 1.1088, "q": 0.000802455430395601, "contrast": "(Space Flight & Infected with Serratia marcescens)v(Ground Control & Infected with Serratia marcescens)", "orientation_sign_applied": 1, "source_file": "GLDS-278_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-588", "log2FC_SF_vs_GC": 0.7577, "q": 2.19936166349336e-164, "contrast": "(Space Flight & y w & Adult & uninfected)v(Ground Control & y w & Adult & uninfected)", "orientation_sign_applied": 1, "source_file": "GLDS-583_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00008", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for HAUS4 in homo_sapiens :: cells?", "gene": "HAUS4", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.6741, "max_abs_log2FC": 2.9456, "max_q": 0.000592, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 0.6741, "q": 0.000591858613711109, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 2.9456, "q": 2.13097310882e-51, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00009", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for PALLD in homo_sapiens :: cells?", "gene": "PALLD", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.5007, "max_abs_log2FC": 2.0294, "max_q": 0.016543, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.0294, "q": 2.4240444829465e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 0.5007, "q": 0.0165429123295117, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00010", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for LPCAT4 in homo_sapiens :: cells?", "gene": "LPCAT4", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.9567, "max_abs_log2FC": 1.8999, "max_q": 0.005513, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 0.9567, "q": 0.00551309949893153, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 1.8999, "q": 8.13734852713775e-30, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00011", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ADCY8 in homo_sapiens :: cells?", "gene": "ADCY8", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.9509, "max_abs_log2FC": 4.4179, "max_q": 0.002521, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -0.9509, "q": 0.0025210963878015, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.4179, "q": 1.82155705736236e-18, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00012", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for CDH6 in homo_sapiens :: cells?", "gene": "CDH6", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.2342, "max_abs_log2FC": 4.0563, "max_q": 1e-06, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 4.0563, "q": 1.90310741345035e-09, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 1.2342, "q": 9.98383358276911e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00013", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AREG in homo_sapiens :: cells?", "gene": "AREG", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.2552, "max_abs_log2FC": 3.4226, "max_q": 2e-06, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -2.2552, "q": 1.85047925166781e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.4226, "q": 1.58156216458821e-09, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00014", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for CH25H in homo_sapiens :: cells?", "gene": "CH25H", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.0092, "max_abs_log2FC": 4.1561, "max_q": 0.027717, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -4.1561, "q": 4.84749031262499e-08, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -2.0092, "q": 0.0277165470218197, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00015", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ANKRD1 in homo_sapiens :: cells?", "gene": "ANKRD1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.1388, "max_abs_log2FC": 4.6152, "max_q": 0.028686, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -1.1388, "q": 0.0286858699668117, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.6152, "q": 1.28544695067175e-58, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00016", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for PNLIPRP3 in homo_sapiens :: cells?", "gene": "PNLIPRP3", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.9689, "max_abs_log2FC": 7.6546, "max_q": 1e-06, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -2.9689, "q": 6.7837541670279e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -7.6546, "q": 1.01505368449196e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00017", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATP1B1 in homo_sapiens :: cells?", "gene": "ATP1B1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.4275, "max_abs_log2FC": 2.9354, "max_q": 7e-06, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 2.9354, "q": 7.18629963196447e-06, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 1.4275, "q": 1.56696197406372e-14, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00018", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for EDN1 in homo_sapiens :: cells?", "gene": "EDN1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.2469, "max_abs_log2FC": 3.2984, "max_q": 0.001767, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -1.2469, "q": 0.00176741038151549, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.2984, "q": 1.31590360973692e-27, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00019", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for CXCL1 in homo_sapiens :: cells?", "gene": "CXCL1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.3756, "max_abs_log2FC": 3.4211, "max_q": 0.0, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -3.4211, "q": 3.57249488033162e-08, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -1.3756, "q": 5.75501913959664e-19, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00020", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for UBE2C in homo_sapiens :: cells?", "gene": "UBE2C", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.8956, "max_abs_log2FC": 5.9754, "max_q": 0.00418, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 0.8956, "q": 0.00418014661577491, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 5.9754, "q": 7.23184503510554e-49, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00021", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ROS1 in homo_sapiens :: cells?", "gene": "ROS1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.8685, "max_abs_log2FC": 4.361, "max_q": 0.0274, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -0.8685, "q": 0.00832481538750964, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -4.361, "q": 0.0274001036745744, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00022", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for RASGEF1B in homo_sapiens :: cells?", "gene": "RASGEF1B", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.4132, "max_abs_log2FC": 3.0411, "max_q": 0.022122, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -3.0411, "q": 2.51376596431375e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -1.4132, "q": 0.0221219603643635, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00023", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for DDX43 in homo_sapiens :: cells?", "gene": "DDX43", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.6693, "max_abs_log2FC": 3.201, "max_q": 0.042168, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 0.6693, "q": 0.0421676486498179, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 3.201, "q": 9.24260087327623e-08, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00024", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for NIM1K in homo_sapiens :: cells?", "gene": "NIM1K", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 2.7281, "max_abs_log2FC": 3.5807, "max_q": 0.0, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -2.7281, "q": 2.51376596431375e-07, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.5807, "q": 2.13937800000273e-13, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00025", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for BEST1 in homo_sapiens :: cells?", "gene": "BEST1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.7178, "max_abs_log2FC": 3.0337, "max_q": 0.003936, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -0.7178, "q": 0.00393607597793105, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -3.0337, "q": 5.49425655699887e-35, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00026", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for WARS1 in homo_sapiens :: cells?", "gene": "WARS1", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.9646, "max_abs_log2FC": 2.6099, "max_q": 3.2e-05, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -2.6099, "q": 3.21357036938446e-05, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -0.9646, "q": 2.16656238293966e-08, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00027", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ANKRD30B in homo_sapiens :: cells?", "gene": "ANKRD30B", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 1.4303, "max_abs_log2FC": 2.5445, "max_q": 0.000135, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": -2.5445, "q": 0.000135384804681194, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": -1.4303, "q": 1.02876215115358e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00028", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for BIRC5 in homo_sapiens :: cells?", "gene": "BIRC5", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.6009, "max_abs_log2FC": 5.4752, "max_q": 0.043023, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 0.6009, "q": 0.0430230616453322, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 5.4752, "q": 3.99621148741775e-50, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00029", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for MCM5 in homo_sapiens :: cells?", "gene": "MCM5", "organism": "homo_sapiens", "tissue": "cells", "context": "homo_sapiens::cells", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-546", "OSD-635"], "min_abs_log2FC": 0.7111, "max_abs_log2FC": 2.469, "max_q": 0.043787, "discordant": false}, "provenance": [{"osd": "OSD-546", "log2FC_SF_vs_GC": 0.7111, "q": 0.043786539734242, "contrast": "(Space Flight & osteogenic)v(Ground Control & osteogenic)", "orientation_sign_applied": 1, "source_file": "GLDS-546_array_differential_expression.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-635", "log2FC_SF_vs_GC": 2.469, "q": 1.48241262813936e-37, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-608_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00030", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for 2810429I04Rik in mus_musculus :: thymus?", "gene": "2810429I04Rik", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.9865, "max_abs_log2FC": 2.7595, "max_q": 0.026832, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.3065, "q": 0.00988474224466204, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -2.7595, "q": 0.0268315495396508, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.9865, "q": 0.00899247696699668, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00031", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Mad2l1 in mus_musculus :: thymus?", "gene": "Mad2l1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 1.1048, "max_abs_log2FC": 1.9379, "max_q": 0.044165, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.1048, "q": 0.0441651390480881, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -1.9379, "q": 7.74616673404573e-12, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.4905, "q": 0.00179684168711342, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00032", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Ska2 in mus_musculus :: thymus?", "gene": "Ska2", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 1.0373, "max_abs_log2FC": 1.6216, "max_q": 0.027895, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.0373, "q": 0.0278950929540556, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -1.6216, "q": 1.04564372100123e-06, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.0511, "q": 0.00978519091575253, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00033", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Snrpa1 in mus_musculus :: thymus?", "gene": "Snrpa1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.5374, "max_abs_log2FC": 0.8276, "max_q": 0.028844, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -0.5374, "q": 0.0288436773903937, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -0.8276, "q": 0.0176937996680454, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.7938, "q": 0.00978519091575253, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00034", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Cd200 in mus_musculus :: thymus?", "gene": "Cd200", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.951, "max_abs_log2FC": 1.566, "max_q": 0.049873, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 0.951, "q": 0.0498732023509274, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.9702, "q": 0.0437234434336739, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.566, "q": 0.00327947687708504, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00035", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Phf6 in mus_musculus :: thymus?", "gene": "Phf6", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.6483, "max_abs_log2FC": 0.9901, "max_q": 0.035009, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -0.9342, "q": 0.019408381488956, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -0.9901, "q": 0.00631935845267518, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.6483, "q": 0.0350093354263148, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00036", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Dcaf11 in mus_musculus :: thymus?", "gene": "Dcaf11", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.4759, "max_abs_log2FC": 0.9518, "max_q": 0.021139, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 0.9518, "q": 0.0211389433990603, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 0.8572, "q": 0.0178104157273343, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 0.4759, "q": 0.00736875727409569, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00037", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Srsf10 in mus_musculus :: thymus?", "gene": "Srsf10", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.5762, "max_abs_log2FC": 1.0245, "max_q": 0.008392, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.0245, "q": 0.00839221269671564, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -0.6388, "q": 0.00227658056251137, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.5762, "q": 0.00472808170259462, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00038", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Ckap5 in mus_musculus :: thymus?", "gene": "Ckap5", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.7077, "max_abs_log2FC": 0.792, "max_q": 0.047367, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -0.7251, "q": 0.0473666720068434, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -0.792, "q": 0.0345630876627913, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.7077, "q": 0.020204550894703, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00039", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Ccdc34 in mus_musculus :: thymus?", "gene": "Ccdc34", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-244", "OSD-421", "OSD-515"], "min_abs_log2FC": 0.8636, "max_abs_log2FC": 1.1024, "max_q": 0.015783, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": -1.1024, "q": 0.0157827358289006, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": -0.9343, "q": 0.0024830915189803, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.8636, "q": 0.00305189970347434, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00040", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Tacc3 in mus_musculus :: thymus?", "gene": "Tacc3", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.1139, "max_abs_log2FC": 2.8124, "max_q": 0.026424, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -2.8124, "q": 2.09329781904681e-13, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.1139, "q": 0.0264239957211769, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00041", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Cenpe in mus_musculus :: thymus?", "gene": "Cenpe", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.3239, "max_abs_log2FC": 2.6926, "max_q": 0.010729, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -2.6926, "q": 4.84846004729226e-23, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.3239, "q": 0.0107286751879968, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00042", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Dlgap5 in mus_musculus :: thymus?", "gene": "Dlgap5", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.3999, "max_abs_log2FC": 3.2554, "max_q": 0.012029, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -3.2554, "q": 2.50684863302674e-10, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.3999, "q": 0.0120290316394132, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00043", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Cdc6 in mus_musculus :: thymus?", "gene": "Cdc6", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 2.1872, "max_abs_log2FC": 4.1382, "max_q": 0.0, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -4.1382, "q": 1.4713028094659e-11, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -2.1872, "q": 2.03433357894445e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00044", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Tekt2 in mus_musculus :: thymus?", "gene": "Tekt2", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.8875, "max_abs_log2FC": 1.9679, "max_q": 0.039173, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 1.8875, "q": 0.0391733855328672, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.9679, "q": 0.0214735036966361, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00045", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Arhgap19 in mus_musculus :: thymus?", "gene": "Arhgap19", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 0.8235, "max_abs_log2FC": 1.9512, "max_q": 0.02743, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -1.9512, "q": 1.01319935816123e-08, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -0.8235, "q": 0.0274296992880217, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00046", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Clmn in mus_musculus :: thymus?", "gene": "Clmn", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.6618, "max_abs_log2FC": 1.6837, "max_q": 0.031154, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 1.6837, "q": 0.0311544945388357, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.6618, "q": 0.00375113068650823, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00047", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Acsbg1 in mus_musculus :: thymus?", "gene": "Acsbg1", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.9223, "max_abs_log2FC": 2.7693, "max_q": 0.028659, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 2.7693, "q": 0.00798882894797825, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.9223, "q": 0.0286589579221083, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00048", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Egfl7 in mus_musculus :: thymus?", "gene": "Egfl7", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.2694, "max_abs_log2FC": 1.6121, "max_q": 0.026764, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 1.6121, "q": 0.0183989790345688, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.2694, "q": 0.0267640909302626, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00049", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for E2f7 in mus_musculus :: thymus?", "gene": "E2f7", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.6145, "max_abs_log2FC": 5.4143, "max_q": 0.000552, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": -5.4143, "q": 7.65819950324144e-07, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": -1.6145, "q": 0.00055194362314036, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00050", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Dzip1l in mus_musculus :: thymus?", "gene": "Dzip1l", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-515"], "min_abs_log2FC": 1.195, "max_abs_log2FC": 1.3118, "max_q": 0.049205, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 1.3118, "q": 0.0492049461726889, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.195, "q": 0.0173109487250399, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00051", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Rab20 in mus_musculus :: thymus?", "gene": "Rab20", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-244", "OSD-421"], "min_abs_log2FC": 0.8943, "max_abs_log2FC": 1.5463, "max_q": 0.041398, "discordant": false}, "provenance": [{"osd": "OSD-244", "log2FC_SF_vs_GC": 0.8943, "q": 0.0413981911394866, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-244_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-421", "log2FC_SF_vs_GC": 1.5463, "q": 0.0282487581887641, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00052", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Tmem38b in mus_musculus :: thymus?", "gene": "Tmem38b", "organism": "mus_musculus", "tissue": "thymus", "context": "mus_musculus::thymus", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-421", "OSD-515"], "min_abs_log2FC": 1.0884, "max_abs_log2FC": 1.3598, "max_q": 0.013817, "discordant": false}, "provenance": [{"osd": "OSD-421", "log2FC_SF_vs_GC": 1.3598, "q": 0.0138174528087688, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-421_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-515", "log2FC_SF_vs_GC": 1.0884, "q": 0.0129138232696747, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-515_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00053", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Arrdc3 in mus_musculus :: liver?", "gene": "Arrdc3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-47", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 1.0433, "max_abs_log2FC": 2.1392, "max_q": 0.019967, "discordant": false}, "provenance": [{"osd": "OSD-47", "log2FC_SF_vs_GC": -1.5302, "q": 9.57579695286791e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-47_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.2124, "q": 0.0036928594562721, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.0433, "q": 0.0199667195853636, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -2.1392, "q": 1.27997250508749e-18, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00054", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Bhlhe40 in mus_musculus :: liver?", "gene": "Bhlhe40", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.5614, "max_abs_log2FC": 1.1311, "max_q": 0.041261, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.5614, "q": 0.0110673244780519, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.7535, "q": 0.041260621174671, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.6033, "q": 0.0281599569474419, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.1311, "q": 0.0327906055000667, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00055", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Arrdc4 in mus_musculus :: liver?", "gene": "Arrdc4", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.4292, "max_abs_log2FC": 0.9803, "max_q": 0.045229, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.9273, "q": 0.00233962014329891, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.6128, "q": 0.00522554829229001, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.4292, "q": 0.0452285296361453, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -0.9803, "q": 0.00389224965260638, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00056", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Tgm1 in mus_musculus :: liver?", "gene": "Tgm1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.6387, "max_abs_log2FC": 1.4035, "max_q": 0.048645, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.6387, "q": 0.0486448684296607, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.6943, "q": 0.0457923588103001, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.9072, "q": 0.00442750512387196, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.4035, "q": 0.00066137853641453, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00057", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Cdkn1a in mus_musculus :: liver?", "gene": "Cdkn1a", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 4, "datasets": ["OSD-25", "OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 1.6626, "max_abs_log2FC": 3.8174, "max_q": 0.000241, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.6626, "q": 0.000240587020347783, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 3.8174, "q": 4.66470531778448e-23, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 3.7449, "q": 1.59813861909408e-10, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.2739, "q": 0.000123595721903947, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00058", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Il1b in mus_musculus :: liver?", "gene": "Il1b", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-173", "OSD-242"], "min_abs_log2FC": 0.7194, "max_abs_log2FC": 3.2372, "max_q": 0.007999, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.7194, "q": 0.00799851345046795, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -3.2372, "q": 5.17149564460895e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": -2.1717, "q": 0.00681593079894784, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00059", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Gadd45b in mus_musculus :: liver?", "gene": "Gadd45b", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-173", "OSD-242"], "min_abs_log2FC": 2.1292, "max_abs_log2FC": 2.502, "max_q": 0.008921, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 2.2018, "q": 1.79265574915128e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.502, "q": 0.00020789797631257, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 2.1292, "q": 0.0089212902613754, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00060", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Hsph1 in mus_musculus :: liver?", "gene": "Hsph1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-48", "OSD-173"], "min_abs_log2FC": 0.9761, "max_abs_log2FC": 1.9583, "max_q": 0.018832, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -1.9583, "q": 4.32814488401046e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -0.9761, "q": 0.0188319285287518, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.5603, "q": 0.000129753124379505, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00061", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Gm11827 in mus_musculus :: liver?", "gene": "Gm11827", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 1.3486, "max_abs_log2FC": 2.5226, "max_q": 0.014798, "discordant": false}, "provenance": [{"osd": "OSD-48", "log2FC_SF_vs_GC": 1.3486, "q": 0.00829237580636506, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.6414, "q": 0.00150859072568114, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.5226, "q": 0.0147982204103798, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00062", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Ranbp3l in mus_musculus :: liver?", "gene": "Ranbp3l", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-48", "OSD-168"], "min_abs_log2FC": 0.4168, "max_abs_log2FC": 1.5781, "max_q": 0.034887, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.4168, "q": 0.0348868090146007, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.5781, "q": 0.0304136899017475, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.3411, "q": 0.00259220429903285, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00063", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Ccn1 in mus_musculus :: liver?", "gene": "Ccn1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.749, "max_abs_log2FC": 1.2345, "max_q": 0.01674, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.749, "q": 0.00965216133918575, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.7509, "q": 0.0167399762526064, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.2345, "q": 0.0128358897234454, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00064", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Apoa4 in mus_musculus :: liver?", "gene": "Apoa4", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-173", "OSD-242"], "min_abs_log2FC": 1.1963, "max_abs_log2FC": 3.1001, "max_q": 2.4e-05, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.1963, "q": 2.38579354543516e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 2.3007, "q": 2.66163152416438e-16, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 3.1001, "q": 1.00091385534054e-05, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00065", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Cldn3 in mus_musculus :: liver?", "gene": "Cldn3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.3418, "max_abs_log2FC": 1.1828, "max_q": 0.006578, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.5856, "q": 0.00657848977580716, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.3418, "q": 0.00255937006031841, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -1.1828, "q": 0.00281873342445947, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00066", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for 9030616G12Rik in mus_musculus :: liver?", "gene": "9030616G12Rik", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-48", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.7449, "max_abs_log2FC": 2.0552, "max_q": 0.023211, "discordant": false}, "provenance": [{"osd": "OSD-48", "log2FC_SF_vs_GC": -0.7449, "q": 0.0232111401486547, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.7945, "q": 0.00716538083918132, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -2.0552, "q": 2.49925706239873e-09, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00067", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Lrfn3 in mus_musculus :: liver?", "gene": "Lrfn3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-48", "OSD-173"], "min_abs_log2FC": 0.5214, "max_abs_log2FC": 1.2062, "max_q": 0.024621, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.5214, "q": 0.000968172576581337, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 1.1264, "q": 0.0246205380391805, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.2062, "q": 0.00132769184299043, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00068", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Sult1e1 in mus_musculus :: liver?", "gene": "Sult1e1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-173", "OSD-242"], "min_abs_log2FC": 2.5799, "max_abs_log2FC": 4.6279, "max_q": 0.002696, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 2.6712, "q": 0.00269574294125189, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 4.6279, "q": 5.16311348476149e-24, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-242", "log2FC_SF_vs_GC": 2.5799, "q": 0.00225272302207961, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-242_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00069", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Slc22a7 in mus_musculus :: liver?", "gene": "Slc22a7", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-48", "OSD-168"], "min_abs_log2FC": 0.8561, "max_abs_log2FC": 1.2269, "max_q": 0.01738, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.8561, "q": 0.0152108767624537, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 1.2269, "q": 0.00374366984527467, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 0.9497, "q": 0.0173803919160983, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00070", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Dclk3 in mus_musculus :: liver?", "gene": "Dclk3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.6212, "max_abs_log2FC": 2.704, "max_q": 0.012295, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.6224, "q": 0.0122954527680988, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -0.6212, "q": 0.00242803929143022, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": -2.704, "q": 4.47348815788434e-11, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00071", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Mrap in mus_musculus :: liver?", "gene": "Mrap", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-48", "OSD-173"], "min_abs_log2FC": 0.7703, "max_abs_log2FC": 1.1798, "max_q": 0.045031, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 1.1798, "q": 0.000118163123462377, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": 0.7703, "q": 0.000659905847672934, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.0314, "q": 0.0450313550799705, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00072", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Lonrf3 in mus_musculus :: liver?", "gene": "Lonrf3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-48", "OSD-168", "OSD-245"], "min_abs_log2FC": 0.7877, "max_abs_log2FC": 1.5043, "max_q": 0.018558, "discordant": false}, "provenance": [{"osd": "OSD-48", "log2FC_SF_vs_GC": 1.4285, "q": 0.0182371002121299, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 1.5043, "q": 6.91532323906276e-05, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-245", "log2FC_SF_vs_GC": 0.7877, "q": 0.0185577634233084, "contrast": "(Space Flight & ~30 day & On Earth & Upon euthanasia)v(Ground Control & ~30 day & On Earth & Upon euthanasia)", "orientation_sign_applied": 1, "source_file": "GLDS-245_rna_seq_differential_expression_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00073", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Atp1b1 in mus_musculus :: liver?", "gene": "Atp1b1", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-47", "OSD-173"], "min_abs_log2FC": 0.6056, "max_abs_log2FC": 1.5471, "max_q": 0.03197, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.8922, "q": 0.00106629486201546, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-47", "log2FC_SF_vs_GC": 0.6056, "q": 0.0319696584263638, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-47_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.5471, "q": 0.00510277327367703, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00074", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Syne3 in mus_musculus :: liver?", "gene": "Syne3", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-48", "OSD-168"], "min_abs_log2FC": 0.3317, "max_abs_log2FC": 1.5465, "max_q": 0.015406, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": -0.3317, "q": 0.015406316668436, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-48", "log2FC_SF_vs_GC": -1.5465, "q": 0.00326837032177572, "contrast": "(Space Flight & Carcass)v(Ground Control & Carcass)", "orientation_sign_applied": 1, "source_file": "GLDS-48_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": -1.0323, "q": 2.84222120977695e-05, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00075", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for Cntrl in mus_musculus :: liver?", "gene": "Cntrl", "organism": "mus_musculus", "tissue": "liver", "context": "mus_musculus::liver", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 3, "datasets": ["OSD-25", "OSD-168", "OSD-173"], "min_abs_log2FC": 0.319, "max_abs_log2FC": 1.453, "max_q": 0.042235, "discordant": false}, "provenance": [{"osd": "OSD-25", "log2FC_SF_vs_GC": 0.319, "q": 0.0422353937196055, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-25_array_differential_expression_GLmicroarray.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-168", "log2FC_SF_vs_GC": 0.6824, "q": 0.000229736050786419, "contrast": "(Space Flight & SpaceX-4 (RR1) & With Spike-in)v(Ground Control & SpaceX-4 (RR1) & With Spike-in)", "orientation_sign_applied": 1, "source_file": "GLDS-168_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-173", "log2FC_SF_vs_GC": 1.453, "q": 0.000211610487160323, "contrast": "(Space Flight)v(Ground Control)", "orientation_sign_applied": 1, "source_file": "GLDS-173_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00076", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATPCA|ATPRX33|PRX33|PRXCA in arabidopsis_thaliana :: seedlings?", "gene": "ATPCA|ATPRX33|PRX33|PRXCA", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.4755, "max_abs_log2FC": 4.3002, "max_q": 0.043497, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.4755, "q": 0.0434968409523138, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 4.3002, "q": 2.60136410890968e-37, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00077", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ESM1 in arabidopsis_thaliana :: seedlings?", "gene": "ESM1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.4406, "max_abs_log2FC": 7.5741, "max_q": 0.010243, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.4406, "q": 0.0102427741242381, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 7.5741, "q": 1.86777516029143e-76, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00078", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for RTP1|UMAMIT36 in arabidopsis_thaliana :: seedlings?", "gene": "RTP1|UMAMIT36", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.848, "max_abs_log2FC": 4.0742, "max_q": 0.0, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.848, "q": 5.36422667303493e-08, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -4.0742, "q": 2.45117945273236e-33, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00079", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AtCLE5|CLE5 in arabidopsis_thaliana :: seedlings?", "gene": "AtCLE5|CLE5", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.8345, "max_abs_log2FC": 3.0911, "max_q": 0.039966, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.8345, "q": 0.0399664595625474, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 3.0911, "q": 0.0353875325502179, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00080", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for UGT79B2 in arabidopsis_thaliana :: seedlings?", "gene": "UGT79B2", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.6406, "max_abs_log2FC": 3.0937, "max_q": 9.2e-05, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 3.0937, "q": 5.33912277966319e-10, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 1.6406, "q": 9.1592648986107e-05, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00081", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for PILS7 in arabidopsis_thaliana :: seedlings?", "gene": "PILS7", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.4575, "max_abs_log2FC": 2.7351, "max_q": 0.000588, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.4575, "q": 0.000587720594706472, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.7351, "q": 1.27346100113746e-07, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00082", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AKT2|AKT2/3|AKT3|KT2/3 in arabidopsis_thaliana :: seedlings?", "gene": "AKT2|AKT2/3|AKT3|KT2/3", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.3856, "max_abs_log2FC": 3.9969, "max_q": 0.002159, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.3856, "q": 0.00215876162964468, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 3.9969, "q": 4.44500927951944e-24, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00083", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATL35 in arabidopsis_thaliana :: seedlings?", "gene": "ATL35", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.6493, "max_abs_log2FC": 3.2533, "max_q": 0.04714, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.6493, "q": 0.0471404475195392, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.2533, "q": 0.00234755037013089, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00084", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for GLP9 in arabidopsis_thaliana :: seedlings?", "gene": "GLP9", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.9439, "max_abs_log2FC": 3.097, "max_q": 0.000914, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -0.9439, "q": 0.000914476483691222, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.097, "q": 1.57677913510982e-11, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00085", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AtBBE11 in arabidopsis_thaliana :: seedlings?", "gene": "AtBBE11", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.5391, "max_abs_log2FC": 3.4445, "max_q": 0.038346, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -0.5391, "q": 0.0383460760951005, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.4445, "q": 2.28999126524848e-34, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00086", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for HMT3 in arabidopsis_thaliana :: seedlings?", "gene": "HMT3", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.8039, "max_abs_log2FC": 2.5205, "max_q": 0.047272, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -0.8039, "q": 0.0472716911629709, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.5205, "q": 7.65911201302991e-20, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00087", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AtWRKY42|WRKY42 in arabidopsis_thaliana :: seedlings?", "gene": "AtWRKY42|WRKY42", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.3078, "max_abs_log2FC": 2.4245, "max_q": 0.045913, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.3078, "q": 0.0459125924803775, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.4245, "q": 1.5290223365154e-09, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00088", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATCB5-C|B5|CB5-C|CYTB5-C in arabidopsis_thaliana :: seedlings?", "gene": "ATCB5-C|B5|CB5-C|CYTB5-C", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.1001, "max_abs_log2FC": 2.8024, "max_q": 0.033119, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.1001, "q": 0.0331186526074284, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 2.8024, "q": 1.2100964357773e-25, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00089", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATNRT3.1|NRT3.1|WR3 in arabidopsis_thaliana :: seedlings?", "gene": "ATNRT3.1|NRT3.1|WR3", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.9168, "max_abs_log2FC": 2.2778, "max_q": 0.0001, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -0.9168, "q": 9.99282493844454e-05, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.2778, "q": 3.81822951350052e-27, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00090", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for GAT|GAT1_2.1 in arabidopsis_thaliana :: seedlings?", "gene": "GAT|GAT1_2.1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.5324, "max_abs_log2FC": 2.6018, "max_q": 0.004397, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -0.5324, "q": 0.00439650422386907, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.6018, "q": 1.3656453859362e-104, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00091", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AGO5|AtAGO5 in arabidopsis_thaliana :: seedlings?", "gene": "AGO5|AtAGO5", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.0958, "max_abs_log2FC": 3.4662, "max_q": 0.008119, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 2.0958, "q": 0.00811905186463798, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 3.4662, "q": 1.00451301605019e-05, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00092", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for CYP76C4 in arabidopsis_thaliana :: seedlings?", "gene": "CYP76C4", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.3031, "max_abs_log2FC": 3.8001, "max_q": 0.020819, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.3031, "q": 0.0208193380546836, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.8001, "q": 0.000808103154339395, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00093", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATHSP22.0|HSP22 in arabidopsis_thaliana :: seedlings?", "gene": "ATHSP22.0|HSP22", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.5626, "max_abs_log2FC": 2.6377, "max_q": 0.046038, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.5626, "q": 0.0460384555132701, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 2.6377, "q": 0.000130566713224773, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00094", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for AtPP2-B2|PP2-B2 in arabidopsis_thaliana :: seedlings?", "gene": "AtPP2-B2|PP2-B2", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 2.3354, "max_abs_log2FC": 3.2986, "max_q": 0.016403, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -2.3354, "q": 0.00109034537769211, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.2986, "q": 0.0164026151030157, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00095", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATBCAT-1|BCAT-1|BCAT1 in arabidopsis_thaliana :: seedlings?", "gene": "ATBCAT-1|BCAT-1|BCAT1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.2869, "max_abs_log2FC": 2.0356, "max_q": 0.000517, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.2869, "q": 0.000516804736230332, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.0356, "q": 9.30747044422495e-22, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00096", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATGLR2.3|GLR2.3 in arabidopsis_thaliana :: seedlings?", "gene": "ATGLR2.3|GLR2.3", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.1151, "max_abs_log2FC": 2.2122, "max_q": 0.000994, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.1151, "q": 0.000994480232924849, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.2122, "q": 1.34439783690327e-08, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00097", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ASY1|ATASY1 in arabidopsis_thaliana :: seedlings?", "gene": "ASY1|ATASY1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.8352, "max_abs_log2FC": 1.909, "max_q": 0.011644, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 1.909, "q": 0.0116438371538182, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 1.8352, "q": 0.00233475633611471, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00098", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for ATGRP-5|ATGRP5|GRP-5|GRP5 in arabidopsis_thaliana :: seedlings?", "gene": "ATGRP-5|ATGRP5|GRP-5|GRP5", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "upregulated", "accept": ["upregulated"], "reject": ["indeterminate", "downregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.9425, "max_abs_log2FC": 2.7971, "max_q": 0.019977, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": 0.9425, "q": 0.0199772675466505, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": 2.7971, "q": 4.13666693298666e-28, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00099", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for DLO1 in arabidopsis_thaliana :: seedlings?", "gene": "DLO1", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 0.8759, "max_abs_log2FC": 3.0979, "max_q": 0.025885, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -0.8759, "q": 0.0258853771518774, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -3.0979, "q": 5.49223735228685e-26, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}
{"id": "OSDR-CTRL-00100", "item_type": "concordant_control", "prompt": "In spaceflight versus ground control, what is the direction of change for EXT18 in arabidopsis_thaliana :: seedlings?", "gene": "EXT18", "organism": "arabidopsis_thaliana", "tissue": "seedlings", "context": "arabidopsis_thaliana::seedlings", "expected": "downregulated", "accept": ["downregulated"], "reject": ["indeterminate", "upregulated"], "evidence": {"n_datasets": 2, "datasets": ["OSD-37", "OSD-321"], "min_abs_log2FC": 1.4883, "max_abs_log2FC": 2.0867, "max_q": 0.004381, "discordant": false}, "provenance": [{"osd": "OSD-37", "log2FC_SF_vs_GC": -1.4883, "q": 0.00438050923366255, "contrast": "(Space Flight & Col-0)v(Ground Control & Col-0)", "orientation_sign_applied": 1, "source_file": "GLDS-37_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}, {"osd": "OSD-321", "log2FC_SF_vs_GC": -2.0867, "q": 2.79150954426651e-11, "contrast": "(Space Flight & Wild Type)v(Ground Control & Wild Type)", "orientation_sign_applied": 1, "source_file": "GLDS-321_rna_seq_differential_expression_rRNArm_GLbulkRNAseq.csv", "gene_id_column": "SYMBOL"}]}